| 1. | Curcumin has been shown to induce a wide variety of tumor cells by several mechanisms , mainly including modulation of the expression of oncogenes and cancer suppressor genes , down - regulation the activation of transcription factors , via many signal transduction pathways , and the modulation of cell cycle . provides an overview of domestic and international apoptosis mechanisms of malign tumor cells induced by curcumin in order to better explore and open up new avenues of cancer treatment
姜黄素能够诱导多种肿瘤细胞系凋亡,其机制主要是调控癌基因和抑癌基因,下调多个转录因子活性,通过多种信号转导途径,诱发细胞周期停滞而诱导细胞凋亡.对近年来姜黄素诱导细胞凋亡的机制进行综述,以便更好地探求和开辟治疗恶性肿瘤的新途径。 |
